Friday, July 15, 2016


Tips Simple benchmark for complex dose finding studies

Principles for evaluating health risks to reproduction, (i) to assess information on the relationship between exposure to environmental pollutants and human health, and to provide guidelines for setting exposure limits;.
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Ractopamine (addendum) (jecfa 53, 2004) - ipcs inchem, Species (strain) duration (route) dose (mg/kg bw per day) noel (mg/kg bw per day) critical effects: mouse (b6c3f 1), 10 of each sex per group: 3 months (oral).

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Perfluorooctanoic acid (pfoa) in drinking water, Rat: single oral dose of 0.1 mg/kg bw; followed for 22 days (m) or 5 days (f) 8.41 ± 1.56 table 2 footnote 1 (m) 0.13 ± 0.04 table 2 footnote 1 (f) kemper, 2003.
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